Evolutionary and Functional Significance of Novel Mutations in MDR-XDR TB

SPH Faculty: Principal Investigator

Faramarz Valafar

Professor[email protected] Laboratory for Pathogenesis of Clinical Drug Resistance and Persistence

Research Project Title

• Evolutionary and Functional Significance of Novel Mutations in MDR-XDR TB

Project Description

• Detection of novel genomic and epigenetic mechanisms of resistance to first and second line anti-TB drugs, mechanism of their emergence, and prevalence.

Location/Study Area

• Sweden, South Africa, India, Moldova, the Philippines, Belgium, Belarus

Collaborators

• Public Health Agency of Sweden, Center for Tuberculosis and Long Disease in Minsk, Stellenbosch University, and more

External Links

• Tuberculosis Research Project Site